Biochemistry (BS)

Summary

Students graduating with a BS in biochemistry have an additional opportunity to have their degree certified by the ASBMB if they chose.  Many graduates pursue post-baccalaureate programs including biochemistry, medicine, pharmacy and dentistry. 

Catalog Year

2024-2025

Degree

Bachelor of Science

Major Credits

80

Total Credits

120

Locations

Mankato

Career Cluster

Science, Technology, Engineering, Mathematics

Accreditation

ASBMB

American Society for Biochemistry and Molecular Biology

Update Your Major

Program Requirements

Required General Education

Study of biological processes at the suborganismal level including cell chemistry, metabolism, reproduction, genetics, and complex tissue physiology. Laboratory and discussion sessions stress problem solving and experimental design.

Prerequisites: none

Goal Areas: GE-03

MATH courses - Choose 8 Credit(s). Choose 2 of the following courses. Note that GE-4 requires 1 course so the remaining credits will be considered restricted elective credits.

Limits, continuity, the derivative and applications, transcendental functions, L'Hopital's Rule, and development of the Riemann integral.

Prerequisites: Satisfy Placement Table in this section, MATH 115 or both MATH 112 and MATH 113 with "C" (2.0) or better.

Goal Areas: GE-04

Techniques of integration, applications of integration, improper integrals, numerical integration, the calculus of parametric curves, and infinite series and sequences.

Prerequisites: MATH 121 with "C" (2.0) or better or consent

An introduction to statistical concepts and methods that is applicable to all disciplines. Topics include descriptive measures of data, probability and probability distributions, statistical inference, tests of hypotheses, confidence intervals, correlation, linear regression, and analysis of variance. The use of statistical software will be emphasized. Prereq: ACT Math sub-score of 19 or higher, successful completion of MATH 098 or appropriate placement scores (see Placement Information under Statistics) Fall, Spring, Summer GE-4

Prerequisites: Satisfy Placement Table in this section, or MATH 098 with grade of P.

Goal Areas: GE-02, GE-04

Major Common Core

Study of biological processes at the organismal level including a survey of life forms (viruses, bacteria, protists, fungi, plants, and animals), their evolution, and ecology. Laboratory and discussion sessions stress problem solving and experimental design.

Prerequisites: none

Introduction to genetic analysis. Topics covered will include those of both classical and modern genetics: population genetics, molecular genetics, genetic manipulation of organisms and selection. Central to this course will be the primacy of the trait as the object of genetics and the development/refinement of the concept of the gene. Lab included.Fall, Spring, Summer

Prerequisites: BIOL 105, BIOL 106, and MATH 112

Introduction to the basic principles of chemistry including atomic and molecular structure, bonding, chemical reactions, stoichiometry, thermodynamics and states of matter. Laboratory will reinforce lecture concepts. Prereq: C or higher in MATH 112 or the equivalent; high school chemistry or C or higher in CHEM 104

Prerequisites: "C" (2.0) or higher in MATH 112 or the equivalent; high school chemistry or "C" (2.0) or higher in CHEM 104.

Goal Areas: GE-02, GE-03

Continuation of the basic principles of chemistry including properties of solutions, kinetics, acids and bases, equilibria, buffers, precipitation reactions, electron transfer reactions, electrochemistry, entropy and free energy. Laboratory will reinforce lecture concepts.

Prerequisites: "C" (2.0) or higher in CHEM 201

The course will cover aspects of the ethical conduct of research, chemical safety, and preparation for a profession related to chemistry or biochemistry.

Prerequisites: CHEM 322

Introduction to the principles of chemical analysis, with emphasis on classical methods of analysis. Lectures will stress the theory of chemical measurements and sample handling. Laboratory exercises will provide students with opportunities to explore calibration methods, method development, and established procedures for volumetric and gravimetric analyses. Basic atomic spectroscopy is also presented.

Prerequisites: "C" (2.0) or higher in CHEM 202

Introduction to organic nomenclature, structure, bonding, chemical reactivity, organic acid-base reactions, mechanisms and stereochemistry. IR, MS, and NMR spectroscopy will be introduced. The chemistry of alkanes, alkyl halides, alkenes, alkynes, and alcohols will be covered. Laboratory illustrates synthetic techniques and the preparation and reactions of functional groups discussed during lecture.

Prerequisites: CHEM 202, "C" (2.0) or higher in CHEM 202.

This course is a continuation Chem 322 and includes organic nomenclature, structure, bonding, chemical reactivity, organic acid-base reactions, and reaction mechanisms; the chemistry of ethers, aromatic and heterocyclic compounds, polyenes, ketones, aldehydes, amines, carboxylic acids and their derivatives, and alpha carbonyl compounds and synthetic transformations is covered.

Prerequisites: CHEM 322 with a "C" (2.0) or higher.

Laboratory will highlight common techniques including recrystallization, melting point determination, simple and fractional distillation, extraction, gas and thin layer chromatography, and chemical and spectroscopic qualitative analysis. Single and multi-step syntheses illustrating aromatic and carbonyl chemistry will be performed.

Prerequisites: CHEM 324

Detailed treatment of thermodynamics and chemical kinetics. Topics include equations of state, laws of thermodynamics, phase and reaction equilibrium, reaction kinetics, and thermodynamic properties of polymers, solutions, and of biochemical and electrochemical processes. C (2.0) or higher in all prerequisites.

Prerequisites: MATH 121, PHYS 211, CHEM 305

Laboratory to accompany CHEM 445. An advanced treatment of measurement theory and data analysis precedes a series of thermodynamic and kinetic experiments designed to complement topics treated in lecture to help students' independence and sophistication in planning, performing, and reporting experimental work.

Prerequisites: CHEM 445

Detailed analysis of the structures, properties, and functions of proteins, carbohydrates, and lipids; introduction to carbohydrate metabolism; theory for the purification and analysis of proteins. Concurrent enrollment in CHEM 465 is recommended.

Prerequisites: BIOL 106, CHEM 324. BIOL 106 or permission "C" (2.0) or higher in all prerequisites.

Detailed analysis of the reactions involved in intermediary metabolism, translation, transcription, and replication.

Prerequisites: CHEM 460

A lecture/laboratory course, which presents methodology and instrumentation used to purify and analyze biomolecules. Techniques include chromatography, radioisotope techniques, polyacrylamide gel electrophoresis, spectrophotometry, and PCR analysis.

Prerequisites: Concurrent registration in CHEM 460 or completion of CHEM 460 with "C" or higher. CHEM 305 is highly recommended.

Students work in teams to solve biochemical research problems by analyzing data from experiments which they design.

Prerequisites: none

In this course, students will develop discipline-specific skills in critical reading and evaluation of the primary and secondary literature, including the use of libraries and databases to identify reliable sources. Work will culminate in a literature review that synthesizes the current state of research in synthetic polymers, biological macromolecules, supramolecular aggregates and/or meso/nanoscale materials with consideration toward future directions. Throughout the course, students will participate in peer review, revision of written work, learn key ethical considerations of writing, develop better writing mechanics and understand different conventions of scientific writing all while increasing their familiarity in the topics above.

Prerequisites: ENG 101, CHEM 324

Capstone course for majors in Chemistry, Biochemistry, and Chemistry Teaching. During this course, students will present their mentored undergraduate research projects OR present a literature review synthesized from primary literature articles. Forums for presentation include an oral presentation and poster presentation.

Prerequisites: CHEM 445 or CHEM 465

General background in physical concepts for those who do not plan advanced study in physics or engineering. Topics include mechanics, fluids, heat and thermodynamics. Lecture and laboratory.

Prerequisites: Either MATH 112 and MATH 113, or MATH 115

Goal Areas: GE-02, GE-03

Includes waves and sound, electricity and magnetism, light and optics, and topics in modern physics. Lecture and laboratory.

Prerequisites: PHYS 211

Molecular or Cell Biology option - Choose 4 Credit(s). Choose 1 course.

An examination of eukaryotic cellular structure, organization and physiology. Lab included.

Prerequisites: BIOL 105 and BIOL 106, BIOL 211

This course will cover both eukaryotic and prokaryotic molecular biology including: DNA and RNA structure, transcription, regulation of gene expression, RNA processing, protein synthesis, DNA replication, mutagenesis and repair, recombination, and insertion elements. A number of important techniques used in recombinant DNA technology will be discussed and practiced.

Prerequisites: BIOL 105, BIOL 106, BIOL 211

Major Restricted Electives

Choose 6 Credit(s). Select from upper-division Biology and Chemistry courses excluding BIOL 481, BIOL 483, BIOL 485, CHEM 479. No more than 3 credits from CHEM 398, CHEM 497, CHEM 498, CHEM 499, BIOL 398, BIOL 497, BIOL 498, or BIOL 499 may count toward Major Restrictive Electives.

Prerequisites: none

Prerequisites: none

Minor

Minor is not required.

4-Year Plan

The 4-Year Plan is a model for completing your degree in a timely manner. Your individual 4-Year plan may change based on a number of variables including transfer courses and the semester/year you start your major. Carefully work with your academic advisors to devise your own unique plan.
* Please meet with your advisor on appropriate course selection to meet your educational and degree goals.

First Year

Fall - 16 Credits

Students in this course approach writing as a subject of study by investigating how writing works across a variety of contexts.

Prerequisites: none

Goal Areas: GE-1A

Limits, continuity, the derivative and applications, transcendental functions, L'Hopital's Rule, and development of the Riemann integral.

Prerequisites: Satisfy Placement Table in this section, MATH 115 or both MATH 112 and MATH 113 with "C" (2.0) or better.

Goal Areas: GE-04

Introduction to the basic principles of chemistry including atomic and molecular structure, bonding, chemical reactions, stoichiometry, thermodynamics and states of matter. Laboratory will reinforce lecture concepts. Prereq: C or higher in MATH 112 or the equivalent; high school chemistry or C or higher in CHEM 104

Prerequisites: "C" (2.0) or higher in MATH 112 or the equivalent; high school chemistry or "C" (2.0) or higher in CHEM 104.

Goal Areas: GE-02, GE-03

Spring - 16 Credits

Study of biological processes at the suborganismal level including cell chemistry, metabolism, reproduction, genetics, and complex tissue physiology. Laboratory and discussion sessions stress problem solving and experimental design.

Prerequisites: none

Goal Areas: GE-03

An introduction to statistical concepts and methods that is applicable to all disciplines. Topics include descriptive measures of data, probability and probability distributions, statistical inference, tests of hypotheses, confidence intervals, correlation, linear regression, and analysis of variance. The use of statistical software will be emphasized. Prereq: ACT Math sub-score of 19 or higher, successful completion of MATH 098 or appropriate placement scores (see Placement Information under Statistics) Fall, Spring, Summer GE-4

Prerequisites: Satisfy Placement Table in this section, or MATH 098 with grade of P.

Goal Areas: GE-02, GE-04

Continuation of the basic principles of chemistry including properties of solutions, kinetics, acids and bases, equilibria, buffers, precipitation reactions, electron transfer reactions, electrochemistry, entropy and free energy. Laboratory will reinforce lecture concepts.

Prerequisites: "C" (2.0) or higher in CHEM 201

Second Year

Fall - 15 Credits

Study of biological processes at the organismal level including a survey of life forms (viruses, bacteria, protists, fungi, plants, and animals), their evolution, and ecology. Laboratory and discussion sessions stress problem solving and experimental design.

Prerequisites: none

Introduction to the principles of chemical analysis, with emphasis on classical methods of analysis. Lectures will stress the theory of chemical measurements and sample handling. Laboratory exercises will provide students with opportunities to explore calibration methods, method development, and established procedures for volumetric and gravimetric analyses. Basic atomic spectroscopy is also presented.

Prerequisites: "C" (2.0) or higher in CHEM 202

Introduction to organic nomenclature, structure, bonding, chemical reactivity, organic acid-base reactions, mechanisms and stereochemistry. IR, MS, and NMR spectroscopy will be introduced. The chemistry of alkanes, alkyl halides, alkenes, alkynes, and alcohols will be covered. Laboratory illustrates synthetic techniques and the preparation and reactions of functional groups discussed during lecture.

Prerequisites: CHEM 202, "C" (2.0) or higher in CHEM 202.

Spring - 12 Credits

Introduction to genetic analysis. Topics covered will include those of both classical and modern genetics: population genetics, molecular genetics, genetic manipulation of organisms and selection. Central to this course will be the primacy of the trait as the object of genetics and the development/refinement of the concept of the gene. Lab included.Fall, Spring, Summer

Prerequisites: BIOL 105, BIOL 106, and MATH 112

The course will cover aspects of the ethical conduct of research, chemical safety, and preparation for a profession related to chemistry or biochemistry.

Prerequisites: CHEM 322

This course is a continuation Chem 322 and includes organic nomenclature, structure, bonding, chemical reactivity, organic acid-base reactions, and reaction mechanisms; the chemistry of ethers, aromatic and heterocyclic compounds, polyenes, ketones, aldehydes, amines, carboxylic acids and their derivatives, and alpha carbonyl compounds and synthetic transformations is covered.

Prerequisites: CHEM 322 with a "C" (2.0) or higher.

Laboratory will highlight common techniques including recrystallization, melting point determination, simple and fractional distillation, extraction, gas and thin layer chromatography, and chemical and spectroscopic qualitative analysis. Single and multi-step syntheses illustrating aromatic and carbonyl chemistry will be performed.

Prerequisites: CHEM 324

Third Year

Fall - 16 Credits

General background in physical concepts for those who do not plan advanced study in physics or engineering. Topics include mechanics, fluids, heat and thermodynamics. Lecture and laboratory.

Prerequisites: Either MATH 112 and MATH 113, or MATH 115

Goal Areas: GE-02, GE-03

Detailed analysis of the structures, properties, and functions of proteins, carbohydrates, and lipids; introduction to carbohydrate metabolism; theory for the purification and analysis of proteins. Concurrent enrollment in CHEM 465 is recommended.

Prerequisites: BIOL 106, CHEM 324. BIOL 106 or permission "C" (2.0) or higher in all prerequisites.

A lecture/laboratory course, which presents methodology and instrumentation used to purify and analyze biomolecules. Techniques include chromatography, radioisotope techniques, polyacrylamide gel electrophoresis, spectrophotometry, and PCR analysis.

Prerequisites: Concurrent registration in CHEM 460 or completion of CHEM 460 with "C" or higher. CHEM 305 is highly recommended.

In this course, students will develop discipline-specific skills in critical reading and evaluation of the primary and secondary literature, including the use of libraries and databases to identify reliable sources. Work will culminate in a literature review that synthesizes the current state of research in synthetic polymers, biological macromolecules, supramolecular aggregates and/or meso/nanoscale materials with consideration toward future directions. Throughout the course, students will participate in peer review, revision of written work, learn key ethical considerations of writing, develop better writing mechanics and understand different conventions of scientific writing all while increasing their familiarity in the topics above.

Prerequisites: ENG 101, CHEM 324

Spring - 15 Credits

Includes waves and sound, electricity and magnetism, light and optics, and topics in modern physics. Lecture and laboratory.

Prerequisites: PHYS 211

Detailed analysis of the reactions involved in intermediary metabolism, translation, transcription, and replication.

Prerequisites: CHEM 460

Students work in teams to solve biochemical research problems by analyzing data from experiments which they design.

Prerequisites: none

Fourth Year

Fall - 14 Credits

Detailed treatment of thermodynamics and chemical kinetics. Topics include equations of state, laws of thermodynamics, phase and reaction equilibrium, reaction kinetics, and thermodynamic properties of polymers, solutions, and of biochemical and electrochemical processes. C (2.0) or higher in all prerequisites.

Prerequisites: MATH 121, PHYS 211, CHEM 305

Laboratory to accompany CHEM 445. An advanced treatment of measurement theory and data analysis precedes a series of thermodynamic and kinetic experiments designed to complement topics treated in lecture to help students' independence and sophistication in planning, performing, and reporting experimental work.

Prerequisites: CHEM 445

Spring - 12 Credits

This course will cover both eukaryotic and prokaryotic molecular biology including: DNA and RNA structure, transcription, regulation of gene expression, RNA processing, protein synthesis, DNA replication, mutagenesis and repair, recombination, and insertion elements. A number of important techniques used in recombinant DNA technology will be discussed and practiced.

Prerequisites: BIOL 105, BIOL 106, BIOL 211

Capstone course for majors in Chemistry, Biochemistry, and Chemistry Teaching. During this course, students will present their mentored undergraduate research projects OR present a literature review synthesized from primary literature articles. Forums for presentation include an oral presentation and poster presentation.

Prerequisites: CHEM 445 or CHEM 465

Policies

First year of coursework for biochemistry majors should include two semesters of chemistry (CHEM 201, CHEM 202), MATH and at least one semester of Biology (BIOL 105). Organic Chemistry should be taken during the second year.

Admission to Major. No formal Admission to Major paperwork is required for Biochemistry. A student can enroll in 300-and 400-level courses after they have declared biochemistry as a first major and successfully completed any pre-requisite paperwork. Students should also have an assigned advisor in the department with whom they have discussed their program.

GPA Policy. Students obtaining a major in biochemistry must maintain an overall GPA of 2.2 in all courses required for their selected program with no more than 4 credits of "D" (1.0) work in chemistry or biochemistry courses.

Residency Requirement: Students must meet a residency requirement. This means that all students who wish to receive either the Biochemistry BA or the Biochemistry BS from Minnesota State Mankato must complete the biochemistry sequence which consists of CHEM 460, CHEM 461, CHEM 465 and CHEM 466 at Minnesota State Mankato. It is important that this sequence be taken during the third (junior) year for all majors.

Elective Credits

  • Courses cannot double-count in the major.
  • Students who use CHEM 498 as elective credits towards their Biochemistry degree must submit a research report to their faculty mentor upon completion of CHEM 498.
  • No more than 3 credits from CHEM 398, CHEM 497, CHEM 498, CHEM 499, BIOL 398, BIOL 497, BIOL 498, or BIOL 499 may count in the major.

P/N Grading Policy. Courses leading to a major or minor in chemistry or biochemistry may not be taken on a P/N basis, except where P/N grading is mandatory.